Quantification of gene expression while taking into account RNA alternative splicing
نویسندگان
چکیده
منابع مشابه
Taking into account nucleosomes for predicting gene expression.
The eukaryotic genome is organized in a chain of nucleosomes that consist of 145-147 bp of DNA wrapped around a histone octamer protein core. Binding of transcription factors (TF) to nucleosomal DNA is frequently impeded, which makes it a challenging task to calculate TF occupancy at a given regulatory genomic site for predicting gene expression. Here, we review methods to calculate TF binding ...
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ژورنال
عنوان ژورنال: Genomics
سال: 2019
ISSN: 0888-7543
DOI: 10.1016/j.ygeno.2018.10.009